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Designer Drugs by M. Foster Olive

By M. Foster Olive

Dressmaker medications and the mind -- Methamphetamine -- Ecstasy -- GHB -- Rohypnol -- Ketamine.; Explains what fashion designer medicines are, their results at the brain and physique, how they're made and disbursed, and legislation concerning those medicinal drugs

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However, in the late 1970s, a biochemist at the University of California at Berkeley named Alexander Shuglin was approached by a student who claimed to have used MDMA to fix a stuttering problem. Shuglin decided to synthesize the drug and take it himself. 1 The chemical structure of Ecstasy (MDMA) is very similar to those of its cousins, amphetamine and methamphetamine. The structure of Ecstasy is shown here, with the structure of amphetamine enclosed in the box. Ecstasy contains an additional carbon ring and a methane (CH3) group.

As can be seen on this graph, the number of emergency room reports more than doubled in the course of two years (1998 and 2000). Although fewer cases were reported in 2001 than 2000, GHB use is still a problem. 05) than the estimate for 2001. GHB is eliminated rapidly from the body, so in the binge GHB user, symptoms of withdrawal may begin within a few hours of the last dose. Despite being eliminated from the body quickly, the withdrawal symptoms may persist for weeks or months. Because GHB use and abuse has only recently become prevalent, treatment programs designed specifically for the GHB addict have not yet been developed.

GHB may also interact with a wellknown chemical messenger in the brain called GABA (gamma amino butyric acid). 1 lists the brain regions where GHB is believed to produce its effects. 1 GHB’s Effect on the Brain EFFECT BRAIN REGION(S) Drowsiness and sleep Frontal cortex, brainstem, hypothalamus Euphoria, positive feelings, reduced inhibitions Frontal cortex, limbic system Hallucinations, increased sexual drive Visual cortex, limbic system Loss of balance, motor impairment Cerebellum Reduced respiration Brainstem Amnesia Hippocampus (limbic system) GHB may also act directly on muscles to produce relaxation and decreased heart rate.

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