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An American Plague: The True and Terrifying Story of the by Jim Murphy

By Jim Murphy

1793, Philadelphia. The nation's capital and the biggest urban in North the United States is devastated by way of an it seems that incurable sickness, reason unknown . . .

In a strong, dramatic narrative, significantly acclaimed writer Jim Murphy describes the disorder referred to as yellow fever and the toll it took at the city's citizens, bearing on the epidemic to the main social and political occasions of the day and to 18th-century scientific ideals and practices. Drawing on first-hand debts, Murphy spotlights the heroic function of Philadelphia's unfastened blacks in battling the disorder, and the Constitutional hindrance that President Washington confronted whilst he used to be compelled to depart the city—and all his papers—while escaping the lethal contagion. the hunt for the fever's factors and medication, no longer chanced on for greater than a century in a while, presents a suspenseful counterpoint to this riveting precise tale of a urban lower than siege.

An American Plague's various awards comprise a Sibert Medal, a Newbery Honor, and designation as a countrywide ebook Award Finalist. completely researched, generously illustrated with interesting archival prints, and unflinching in its dialogue of clinical info, this publication deals a glimpse into the stipulations of yankee towns on the time of our nation's beginning whereas drawing well timed parallels to modern day epidemics. Bibliography, map, index.

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Source: Clinica Chimica Acta; International Journal of Clinical Chemistry. 1970 June; 28(3): 397-402. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=5450163 • Immunochemical characterization of human beta-D-N-acetyl hexosaminidase from normal individuals and patients with Tay-Sachs disease. I. Antigenic differences between hexosaminidase A and hexosaminidase B. Author(s): Bartholomew WR, Rattazzi MC. Source: Int Arch Allergy Appl Immunol. 1974; 46(4): 512-24. No Abstract Available. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=4132060 • Immunohistochemical demonstration of GM2-ganglioside in the central nervous system of a 19-week-old fetus of Tay-Sachs disease.

Author(s): Landels EC, Ellis IH, Bobrow M, Fensom AH. Source: Journal of Medical Genetics. 1991 February; 28(2): 101-9. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=1825851 • Tay-Sachs disease in an Israeli Arab family: Trp26-->stop in the alpha-subunit of hexosaminidase A. Author(s): Drucker L, Navon R. Source: Human Mutation. 1993; 2(5): 415-7. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=8257995 • Tay-Sachs disease in Moroccan Jews: deletion of a phenylalanine in the alphasubunit of beta-hexosaminidase.

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