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Alzheimer's Disease (Genes & Disease) by Evelyn B Kelly

By Evelyn B Kelly

Alzheimer's disorder is the most typical kind of dementia in older adults, robbing them in their minds and dignity. featuring a historical past of the , this name appears on the human genome and explores how the items of the Alzheimer's puzzle are commencing to healthy jointly.

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Additional info for Alzheimer's Disease (Genes & Disease)

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In37 37 8/21/08 4:48:15 PM 38 Alzheimer’s Disease difficulty walking and may suffer more easily from complications of other diseases, such as pneumonia. Signs of this stage include verbal outbursts, behavioral difficulties, WHAT LAW ENFORCEMENT PERSONNEL NEED TO KNOW The Alzheimer’s Association trains law enforcement officers to deal with situations involving people with AD. The following includes some pertinent information. People with AD may wander off: Average distance of locating the individual alive is 0–5 miles.

In42 42 8/21/08 4:48:17 PM Meet the Human Genome 43 of human genes. Many diseases of genetic origin can be traced to a change or mutation in only one gene. The genetics of AD is not so simple and involves many genes. To grasp how genes play a role in AD, this chapter includes a primer of the fundamentals of genetics, with an explanation of some of the important concepts—genes, DNA, proteins, chromosomes, transcription, and codons. WHAT IS A GENE? In 1663, Robert Hooke, a British scientist, peered through his crude microscope at a piece of cork and was interested in what he saw.

In61 61 Scientists conduct basic research when they look for what causes a condition. This research is mostly done on animals. 8/21/08 4:48:27 PM 62 Alzheimer’s Disease ◆ ◆ Applied research occurs when the scientists, building on basic information, begin to apply what they know to the disease. At this stage, they may test drugs or other treatments on animals. Clinical research is done on humans. It starts with only a few people to test for the safety of a drug. Then more and more people are used.

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