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Age-related Macular Degeneration Diagnosis and Treatment by Daniel T. Kasuga B.S. (auth.), Allen C. Ho, Carl D. Regillo

By Daniel T. Kasuga B.S. (auth.), Allen C. Ho, Carl D. Regillo (eds.)

Age-related Macular Degeneration analysis and Treatment offers —for the retina expert, basic eye care specialist, imaginative and prescient scientist, and people education in those areas—an replace at the present knowing of age-related macular degeneration (AMD), pathophysiology, using diagnostic checks, and the administration of either non-neovascular and neovascular AMD. It additionally seems into the long run with capability treatments which are now less than research in medical trials, and eventually, covers the clinical economics and societal effect of this significant public healthiness factor. specific positive factors of this ebook:

· Written by way of best specialists within the field

· Concise but hugely illustrated and functional textual content that publications the clinician via analysis and remedy of the top explanation for blindness in older Americans

· Covers prognosis and cures for either neovascular and non-neovascular age-related macular degeneration (AMD), in addition to much less universal varieties of non-age-related macular degeneration

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Extra info for Age-related Macular Degeneration Diagnosis and Treatment

Sample text

Although the finding of isolated small drusen with distinct borders (hard drusen) in an elderly patient is not worrisome to the clinician, the findings should be documented and followed. Isolated drusen do not account for significant vision loss [10]. Drusen are dynamic and can spontaneously disappear resulting in overlying atrophy of the RPE [40]. Clinically when drusen are either larger than 63 m(mu)m, associated with other changes such as RPE hyper- and hypopigmentation, with vision loss below 20/30, or when soft drusen begin to coalesce, the dialogue should be started with the patients concerning the diagnosis of dry AMD.

Isolated drusen do not account for significant vision loss [10]. Drusen are dynamic and can spontaneously disappear resulting in overlying atrophy of the RPE [40]. Clinically when drusen are either larger than 63 m(mu)m, associated with other changes such as RPE hyper- and hypopigmentation, with vision loss below 20/30, or when soft drusen begin to coalesce, the dialogue should be started with the patients concerning the diagnosis of dry AMD. Macular changes in AMD 32 are almost always present in both eyes although frequently are asymmetric.

Drusen result in thickening of the Bruch’s membrane and RPE degeneration. 2). Different types of drusen include: Soft drusen — yellow lesions with poorly defined edges. They are usually found in people over 55 years of age and represent shallow RPE detachments. These drusen lead to RPE atrophy, photoreceptor degeneration, and predispose to CNV [6–8]. 3). Drusen can be stable, can disappear, can progress to geographic atrophy, or progress to neovascular AMD. High-risk drusen characteristics for progression to neovascular AMD include drusen number (>5), size (>63 m(mu)m), type (soft), confluence, and associated hyperpigmentation [11–14].

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