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Achilles Tendon by Andrej Čretnik

By Andrej Čretnik

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McBride, J. , & McCauley, G. O. (2010). Relationship between muscle strength, power and stiffness and running economy in trained male runners. International journal of sports physiology and performance, 5(2), 249– 261. Egli RJ, Southam L, Wilkins JM, Lorenzen I, Pombo-Suarez M, Gonzalez A, Carr A, Chapman K, and Loughlin J. (2009). Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism. Arthritis & Rheumatism 60: 2055-2064. , & Birk, D. E. (2000). Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons.

Current and future research using human molecular genetics and other biological techniques will play an important part in elucidating the mechanisms and developing more appropriate risk models. Fig. 2. A schematic illustrating how proposed molecular and biological mechanisms could more accurately describe intrinsic component for Achilles tendon injury risk. In this hypothetical model, inter-individual variations in the biochemical and mechanical properties of the tendon, skeletal muscle and other tissues, as well as, other biological structures, systems and processes cause susceptibility to Achilles tendon injuries.

Journal of Applied Physiology, 104: 379–385. Bornstein P, Armstrong, L. , Hankenson, K. , Kyriakides, T. , & Yang, Z. (2000). Thrombospondin 2, a matricellular protein with diverse functions. Matrix biology : journal of the International Society for Matrix Biology, 19(7), 557–568. , Schwellnus, M. , & Collins, M. (2011a). Range of motion measurements diverge with increasing age for COL5A1 genotypes. Scandinavian Journal of Medicine & Science in Sports. , Schwellnus, M. , & Collins, M. (2011b). The COL5A1 gene, ultra-marathon running performance and range of motion.

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